Effect of timing of reoperation on survival in patients with recurrent glioblastoma: retrospective multicentric descriptive study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F23%3A73622954" target="_blank" >RIV/61989592:15110/23:73622954 - isvavai.cz</a>

Result on the web

<a href="http://hhttps://www.mdpi.com/2072-6694/15/9/2530" target="_blank" >http://hhttps://www.mdpi.com/2072-6694/15/9/2530</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/cancers15092530" target="_blank" >10.3390/cancers15092530</a>

Result language

angličtina

Original language name

Effect of timing of reoperation on survival in patients with recurrent glioblastoma: retrospective multicentric descriptive study

Original language description

disappearance; (2) The patient&apos;s clinical condition was satisfactory (pcs ≥ 70 % and PS Who ≤ gr. 2); (3) the tumor was located without multifocality; (4) The minimum expected reducing tumor volume was above 80 %. The one -dimensional Cox&apos;s regression analysis of postoperative survival (PSS) revealed a statistically significant influence of reoperation on PSS from Prague 16 months to the first operation. Cox&apos;s regression models that stratified carnof scores with age regulations confirmed a statistically significant improvement in PSS for threshold values of time to progression (TTP) 22 and 24 months. Groups of patients showing the first recurrence in the 22nd and 24th months had better survival than those showing earlier recurrence. In the 22-month age group HR 0.5 s 95% CI (0.27, 0.96) and p-value 0.036. In a 24-month-old group, HR 0.5 s 95% CI (0.25, 0.96) and p-value 0.039 were HR 0.5 s 95% CI (0.25, 0.96). Patients with the longest survival were also the best candidates for repeated surgery. The later glioblastoma recurrence was associated with a higher survival after reoperation.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30212 - Surgery

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Cancers

ISSN

2072-6694

e-ISSN

—

Volume of the periodical

15

Issue of the periodical within the volume

9

Country of publishing house

CH - SWITZERLAND

Number of pages

1

Pages from-to

2530

UT code for WoS article

000987086900001

EID of the result in the Scopus database

2-s2.0-85159559808