Evidence-based commentary on the diagnosis, management, and further research of degenerative cervical spinal cord compression in the absence of clinical symptoms of myelopathy

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F24%3A73625261" target="_blank" >RIV/61989592:15110/24:73625261 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/24:00079930 RIV/00098892:_____/24:10158659 RIV/00216224:14110/24:00139940
Result on the web
<a href="https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1341371/full" target="_blank" >https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1341371/full</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/fneur.2024.1341371" target="_blank" >10.3389/fneur.2024.1341371</a>

Result language
angličtina
Original language name
Evidence-based commentary on the diagnosis, management, and further research of degenerative cervical spinal cord compression in the absence of clinical symptoms of myelopathy
Original language description
Degenerative cervical myelopathy (DCM) represents the final consequence of a series of degenerative changes in the cervical spine, resulting in cervical spinal canal stenosis and mechanical stress on the cervical spinal cord. This process leads to subsequent pathophysiological processes in the spinal cord tissues. The primary mechanism of injury is degenerative compression of the cervical spinal cord, detectable by magnetic resonance imaging (MRI), serving as a hallmark for diagnosing DCM. However, the relative resilience of the cervical spinal cord to mechanical compression leads to clinical-radiological discordance, i.e., some individuals may exhibit MRI findings of DCC without the clinical signs and symptoms of myelopathy. This degenerative compression of the cervical spinal cord without clinical signs of myelopathy, potentially serving as a precursor to the development of DCM, remains a somewhat controversial topic. In this review article, we elaborate on and provide commentary on the terminology, epidemiology, natural course, diagnosis, predictive value, risks, and practical management of this condition—all of which are subjects of ongoing debate.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30210 - Clinical neurology

Project
<a href="/en/project/NU22-04-00024" target="_blank" >NU22-04-00024: Quantitative magnetic resonance imaging parameters as predictors of outcome of non-myelopathic degenerative cervical cord compression: a longitudinal study</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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