POLYPEPTIDES MIMICKING EPITOPE OF BROADLY NEUTRALIZING ANTIBODY VRC01 AS ANTIGENS FOR A VACCINE PREVENTING HIV-1 INFECTION
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F24%3A73629374" target="_blank" >RIV/61989592:15110/24:73629374 - isvavai.cz</a>
Result on the web
<a href="https://worldwide.espacenet.com/patent/search/family/073995648/publication/US2022402978A1?q=PCT%2FCZ2020%2F050066" target="_blank" >https://worldwide.espacenet.com/patent/search/family/073995648/publication/US2022402978A1?q=PCT%2FCZ2020%2F050066</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
POLYPEPTIDES MIMICKING EPITOPE OF BROADLY NEUTRALIZING ANTIBODY VRC01 AS ANTIGENS FOR A VACCINE PREVENTING HIV-1 INFECTION
Original language description
The present invention provides a polypeptide mimicking epitope of glycoprotein gp120 of HIV-1 virus, which is recognized by a paratope of broadly neutralizing antibody VRC01, has the length up to 100 amino acid residues and contains an amino acid sequence:X1YKNX2INX3AX4X5VX6X7VKRX8IDX9ILAX10LP (SEQ ID NO. 1), , in which:X1 is selected from amino acids A, N, R;X2 is selected from amino acids A, R, D;X3 is selected from amino acids R, V, P;X4 is selected from amino acids V, L, S;X5 is selected from amino acids T, G, R;X6 is selected from amino acids G, T;X7 is selected from amino acids L, A;X8 is selected from amino acids V, I;X9 is selected from amino acids G, A, R;X10 is selected from amino acids R, A, G;with a directly attached alpha-helical structure at the N-terminus or C-terminus.
Czech name
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Czech description
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Classification
Type
P - Patent
CEP classification
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OECD FORD branch
30102 - Immunology
Result continuities
Project
<a href="/en/project/EF16_025%2F0007397" target="_blank" >EF16_025/0007397: Recombinant Biotechnology and Immunotherapy Centre</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Patent/design ID
CN114729008B
Publisher
CN002 -
Publisher name
Patent Office - State Intellectual Property Office of the Peoples` Republic of China (SIPO)
Place of publication
Beijing
Publication country
CN - CHINA
Date of acceptance
Jul 19, 2024
Owner name
UNIVERZITA PALACKEHO V OLOMOUCI
Method of use
A - Výsledek využívá pouze poskytovatel
Usage type
A - K využití výsledku jiným subjektem je vždy nutné nabytí licence