Cognitive impairment, neurodegenerative disorders, and olfactory impairment: A literature review

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15120%2F24%3A73626472" target="_blank" >RIV/61989592:15120/24:73626472 - isvavai.cz</a>
Alternative codes found
RIV/61988987:17110/23:A2502NEK RIV/61989592:15110/24:73626472
Result on the web
<a href="https://otolaryngologypl.com/article/536158/en" target="_blank" >https://otolaryngologypl.com/article/536158/en</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5604/01.3001.0053.6158" target="_blank" >10.5604/01.3001.0053.6158</a>

Result language
angličtina
Original language name
Cognitive impairment, neurodegenerative disorders, and olfactory impairment: A literature review
Original language description
Introduction: The early detection and diagnosis of dementia are of key importance in treatment, slowing disease progression,or suppressing symptoms. The possible role of changes in the sense of smell is considered with regard to potential markers forearly detection of Alzheimer’s disease (AD).Materials and methods: A literature search was conducted using the electronic databases PubMed, Scopus, and Web of Sciencebetween May 30, 2022 and August 2, 2022. The term “dementia” was searched with keyword combinations related to olfaction.Results: A total of 1,288 records were identified through the database search. Of these articles, 49 were ultimately included inthe analysis. The results showed the potential role of changes in the sense of smell as potential biomarkers for early detectionof AD. Multiple studies have shown that olfactory impairment may be observed in patients with AD, PD, MCI, or other typesof dementia. Even though smell tests are able to detect olfactory loss caused by neurodegenerative diseases, they cannotreliably distinguish between certain diseases.Conclusions: In individuals with cognitive impairment or neurodegenerative diseases, olfactory assessment has repeatedlybeen reported to be used for early diagnosis, but not for differential diagnosis.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30302 - Epidemiology

Project
<a href="/en/project/NU20-09-00119" target="_blank" >NU20-09-00119: Possible influence of atherosclerosis on dementia development</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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