Post-Stroke Fatigue in Patients at 3 Months After Ischemic Stroke: Analysis From the FRAILTY Study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15120%2F25%3A73632621" target="_blank" >RIV/61989592:15120/25:73632621 - isvavai.cz</a>

Alternative codes found

RIV/00098892:_____/25:10159590 RIV/61989592:15110/25:73632621

Result on the web

<a href="https://journals.sagepub.com/doi/10.1177/23779608251400226" target="_blank" >https://journals.sagepub.com/doi/10.1177/23779608251400226</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1177/23779608251400226" target="_blank" >10.1177/23779608251400226</a>

Result language

angličtina

Original language name

Post-Stroke Fatigue in Patients at 3 Months After Ischemic Stroke: Analysis From the FRAILTY Study

Original language description

Post-stroke fatigue (PSF) is a known sequel after ischemic stroke (IS), which affects quality of life (QoL), however its incidence and contributing factors remain controversial or not enough established, especially in younger population in working age. To assess PSF in patients in working age (18–65 years) at 3 months after IS and evaluate its possible association to other factors. Consecutive patients with IS in working age enrolled in the prospective FRAILTY (Factors Affecting the Quality of Life After Ischemic Stroke in Young Adults; ClinicalTrials.gov: NCT04839887) were analyzed. PSF was assessed using Fatigue Severity Scale (FSS) and Neuro_QoL_Fatigue scale, post-stroke depression (PSD) and anxiety (PSA) using Hospital Anxiety and Depression Scale at 3 months after IS. QoL was evaluate using Stroke Impact Scale (SIS), version 3.0. Logistic regression analysis (LRA) was performed to identify possible predictors of PSF. In total, 150 (54.0% males, mean age 51.2 ± 8.9 years) were analyzed and 132 (88%) had excellent clinical outcome after 3 months. PSF, based on the FSS, was present in 55.3% of patients and severe PSF in 41.3% of them. LRA showed the significant association between SIS domains memory, emotions, communication, mobility and participation and the presence of severe PSF (FSS score &gt; 5). PSD and PSA were found as other predictors of severe PSF. No association was found between PSF and age, sex, and clinical outcome. Despite overall excellent clinical outcome, severe PSF occurred in 41.3% of patients in working age after 3 months post-stroke. PSF affected strongly QoL and may have close relationship to psychosocial factors and cognition. Routine screening for PSF should be incorporated into post-stroke follow up, especially for working-age patients.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30307 - Nursing

Project

<a href="/en/project/NU22-09-00021" target="_blank" >NU22-09-00021: Factors affecting the quality of life after ischemic stroke in young adults: a prospective study in young patients under age 50 years after ischemic stroke in Czech Republic</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

SAGE Open Nursing

ISSN

2377-9608

e-ISSN

2377-9608

Volume of the periodical

2025

Issue of the periodical within the volume

11

Country of publishing house

US - UNITED STATES

Number of pages

10

Pages from-to

23779608251400226

UT code for WoS article

001627003200001

EID of the result in the Scopus database

2-s2.0-105023163535