Influence of Disease Severity on Fatigue in Patients with Parkinson's Disease Is Mainly Mediated by Symptoms of Depression

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15260%2F13%3A33147227" target="_blank" >RIV/61989592:15260/13:33147227 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1159/000351779" target="_blank" >http://dx.doi.org/10.1159/000351779</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1159/000351779" target="_blank" >10.1159/000351779</a>

Result language

angličtina

Original language name

Influence of Disease Severity on Fatigue in Patients with Parkinson's Disease Is Mainly Mediated by Symptoms of Depression

Original language description

Purpose: Fatigue is a frequent non-motor complaint of patients with Parkinson's disease (PD). Despite increasing knowledge on fatigue, the factors leading to its development are still not recognised. The aim of this investigation was to test, using structural equation modelling, the hypothesis that the influence of disease severity on fatigue is mediated by symptoms of depression in patients with PD. Method: The sample consisted of 190 PD patients (93 men, 48.9%, mean age 68.2 +/- 9.3 years, mean disease duration 6.4 +/- 4.7 years) recruited from hospitals and outpatient clinics in the East Slovakia region. The Multidimensional Fatigue Inventory, the Hospital Anxiety and Depression Scale and the Unified Parkinson's Disease Rating Scale were used. LISREL was used to analyse the data. Results: Disease severity was directly associated with symptoms of depression (beta = 0.26) and directly affected fatigue in terms of increased levels of general fatigue (beta = 0.35), physical fatigue (bet

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FQ - Public health system, social medicine

OECD FORD branch

—

Project

<a href="/en/project/EE.2.3.20.0063" target="_blank" >EE.2.3.20.0063: Social determinants of health among social and health disadvantaged groups of population</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European neurology

ISSN

0014-3022

e-ISSN

—

Volume of the periodical

70

Issue of the periodical within the volume

3-4

Country of publishing house

CH - SWITZERLAND

Number of pages

9

Pages from-to

201-209

UT code for WoS article

000326135500017

EID of the result in the Scopus database

—