Melatonin treatment in the prevention of postoperative delirium in cardiac surgery patients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15260%2F15%3A33156077" target="_blank" >RIV/61989592:15260/15:33156077 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.5114/kitp.2015.52853" target="_blank" >http://dx.doi.org/10.5114/kitp.2015.52853</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5114/kitp.2015.52853" target="_blank" >10.5114/kitp.2015.52853</a>

Result language

angličtina

Original language name

Melatonin treatment in the prevention of postoperative delirium in cardiac surgery patients

Original language description

INTRODUCTION: Post-cardiac surgery delirium is a severe complication. The circadian rhythm of melatonin secretion has been shown to be altered postoperatively. AIM OF THE STUDY: It was hypothesized that restoring normal sleeping patterns with a substancethat is capable of resynchronizing circadian rhythm such as exogenous administration of melatonin may possibly reduce the incidence of postoperative delirium. MATERIAL AND METHODS: This paper represents a prospective clinical observational study. Two consecutive groups of 250 consecutive patients took part in the study. Group A was the control group and group B was the melatonin group. In group B, the patients received prophylactic melatonin treatment. The main objectives were to observe the incidenceof delirium, to identify any predictors of delirium, and to compare the two groups based on the delirium incidence. RESULTS: The incidence of delirium was 8.4% in the melatonin group vs. 20.8% in the control group (p = 0.001). Predictors

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery

ISSN

1731-5530

e-ISSN

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Volume of the periodical

12

Issue of the periodical within the volume

2

Country of publishing house

PL - POLAND

Number of pages

8

Pages from-to

126-33

UT code for WoS article

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EID of the result in the Scopus database

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