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5-Substituted 6-azauracils XVII. Synthesis of 5-(m-tolyl)-6-azauracil

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F00%3A00000982" target="_blank" >RIV/61989592:15310/00:00000982 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    5-Substituted 6-azauracils XVII. Synthesis of 5-(m-tolyl)-6-azauracil

  • Original language description

    7-Methylisatin (I) was converted to appropriate senicarbazone. Its alkaline recyklization afforded 5-(2-amino-3-methyl)-6-azauracil. Its diazotation and subsequent redictive elimination of diazonium group led to the 5-(m-tolyl)-6-azauracil. Reaction of diazotated amine with ethyl cyanoacetylcarbamate afforded appropriate hydrazone. After reaction with bicarbonate this compound was converted to 1-[2-(6-azauracil-5-yl)-6-methylphenyl]-6-azauracil-5-carbonitrile. Cyclization of 5-(2-amino-3-methyl)-6-azauracil afforded 3,5-dihydro-5H-6-methyl-[1,2,4]-triazino[5,6-b]indole-3-one.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CC - Organic chemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2000

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Acta Universitatis Palackianae Olomucensis, Facultas Rerum Naturalium, Chemica

  • ISSN

    0232-0061

  • e-ISSN

  • Volume of the periodical

    39

  • Issue of the periodical within the volume

    NA

  • Country of publishing house

    XX - stateless person

  • Number of pages

    6

  • Pages from-to

  • UT code for WoS article

  • EID of the result in the Scopus database