Recent news related to substrates and inhibitors of plant copper amine oxidases
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F02%3A00001661" target="_blank" >RIV/61989592:15310/02:00001661 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Recent news related to substrates and inhibitors of plant copper amine oxidases
Original language description
Plant copper amine oxidases (CAOs; EC 1.4.3.6) belong to the quinoprotein family. Besides the cofactor topaquinone, they also contain cupric ions participating in the reaction. Numerous substrates and inhibitors of plant CAOs have been reported up to date. We studied interactions of pea seedling enzyme (PSAO) with several artificial amine compounds that have not yet been analysed in this way and whose structure mimic natural polyamine substrates. In addition, our attention was paid to the evaluation ofinhibition potency of sedamine alkaloids and various pyridine-derived oximes. 1,4-Bis(3-aminopropyl)piperazine, N,N´-bis(3-aminopropyl)-trans-2-butene-1,4-diamine and 3-oxapentane-1,5-diamine (OPD) were found to be substrates of PSAO. The corresponding enzyme kinetics was measured, the reaction stoichiometry analysed and rapid-scanning spectrophotometry applied to investigate the reaction mechanism. The identity of the main product of OPD conversion was confirmed by several analytical me
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA203%2F00%2FD119" target="_blank" >GA203/00/D119: Structure and properties of endogenous amine oxidase inhibitor from bean seedlings and its analogues</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2002
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
30rd International Symposium on Vitamin B6, PQQ, Carbonyl Catalysis and quinoproteins
ISBN
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ISSN
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e-ISSN
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Number of pages
60
Pages from-to
37
Publisher name
University of Southampton
Place of publication
Southampton
Event location
Southampton
Event date
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Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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