Characterization of Pseudacyclins A-E, a Suite of Cyclic Peptides Produced Pseudallescheria boydii

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F10%3A10213291" target="_blank" >RIV/61989592:15310/10:10213291 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15110/10:10213291
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Characterization of Pseudacyclins A-E, a Suite of Cyclic Peptides Produced Pseudallescheria boydii
Original language description
Pseudallescheria boydii sensu lato is an emerging fungal pathogen causing fatal infections in both immunocompromised and immunocompetent hosts. In this work, two P. boydii isolates (human and animal origin) have been identified as being producers of cyclic peptides. Five putative nonribosomal peptides with a unique structure, which have been named pseudacyclins, were characterized by nuclear magnetic resonance spectroscopy and mass spectrometry. The most abundant representative of the pseudacyclins wasquantified also on fungal spores. The presence of these peptides on inhaled fungal spores creates the possibility for exploitation of pseudacyclins as early indicators of fungal infections caused by Pseudallescheria species.
Czech name
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Czech description
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Project
<a href="/en/project/LC07017" target="_blank" >LC07017: Oncoproteomics Centre</a>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP) Z - Vyzkumny zamer (s odkazem do CEZ) S - Specificky vyzkum na vysokych skolach

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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