Electrochemical oxidation of berberine and mass spectrometric identification of its oxidation products

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F12%3A33142149" target="_blank" >RIV/61989592:15310/12:33142149 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15110/12:33142149

Result on the web

<a href="http://dx.doi.org/10.1016/j.bioelechem.2011.09.002" target="_blank" >http://dx.doi.org/10.1016/j.bioelechem.2011.09.002</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.bioelechem.2011.09.002" target="_blank" >10.1016/j.bioelechem.2011.09.002</a>

Result language

angličtina

Original language name

Electrochemical oxidation of berberine and mass spectrometric identification of its oxidation products

Original language description

Electrochemical oxidation of the isoquinoline alkaloid berberine in aqueous medium was studied by cyclic and differential pulse voltammetry at a glassy carbon electrode (GCE). Two anodic peaks of the quaternary form of berberine were observed at +1.2 V and +1.4 V (vs. SCE) in acidic and neutral solutions. When the anodic polarization exceeded the value of +1.1 V. the redox active film is formed on the GCE surface. The formation of adsorbed film was well-documented by quasireversible redox couple at +0.25 V which was studied in redox cycling experiments. In alkaline medium, a new anodic peak at +0.5 V appeared due to oxidation of berberine pseudobase to 8-oxoberberine. Solutions of berberine at different pH were subjected to controlled potential electrolysis on platinum gauze electrode and analyzed using liquid chromatography (HPLC) equipped with electrospray ionization/quadrupole time-of-flight mass spectrometry. The main water soluble monomeric product of berberine oxidation under phy

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CG - Electrochemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Bioelectrochemistry

ISSN

1567-5394

e-ISSN

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Volume of the periodical

87

Issue of the periodical within the volume

SI

Country of publishing house

CH - SWITZERLAND

Number of pages

6

Pages from-to

15-20

UT code for WoS article

000309033000004

EID of the result in the Scopus database

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