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Energetics, conformation, and recognition of DNA duplexes containing a major adduct of antitumor azolato-bridged dinuclear Pt II complex.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F12%3A33142311" target="_blank" >RIV/61989592:15310/12:33142311 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.bbagen.2012.05.014" target="_blank" >http://dx.doi.org/10.1016/j.bbagen.2012.05.014</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.bbagen.2012.05.014" target="_blank" >10.1016/j.bbagen.2012.05.014</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Energetics, conformation, and recognition of DNA duplexes containing a major adduct of antitumor azolato-bridged dinuclear Pt II complex.

  • Original language description

    The experimental evidence demonstrates why the major DNA adducts of the new anticancer azolato-bridged dinuclear PtII complexes are poor substrates for DNA repair observed in a previously published report. The relative resistance to DNA repair explains why these platinum complexes show major pharmacological advantages over cisplatin in tumor cells.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BO - Biophysics

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biochimica et Biophysica Acta - General Subjects

  • ISSN

    0304-4165

  • e-ISSN

  • Volume of the periodical

    1820

  • Issue of the periodical within the volume

    10

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    10

  • Pages from-to

    1502-1511

  • UT code for WoS article

    000307369700008

  • EID of the result in the Scopus database