Energetics, conformation, and recognition of DNA duplexes containing a major adduct of antitumor azolato-bridged dinuclear Pt II complex.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F12%3A33142311" target="_blank" >RIV/61989592:15310/12:33142311 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.bbagen.2012.05.014" target="_blank" >http://dx.doi.org/10.1016/j.bbagen.2012.05.014</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.bbagen.2012.05.014" target="_blank" >10.1016/j.bbagen.2012.05.014</a>
Alternative languages
Result language
angličtina
Original language name
Energetics, conformation, and recognition of DNA duplexes containing a major adduct of antitumor azolato-bridged dinuclear Pt II complex.
Original language description
The experimental evidence demonstrates why the major DNA adducts of the new anticancer azolato-bridged dinuclear PtII complexes are poor substrates for DNA repair observed in a previously published report. The relative resistance to DNA repair explains why these platinum complexes show major pharmacological advantages over cisplatin in tumor cells.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BO - Biophysics
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biochimica et Biophysica Acta - General Subjects
ISSN
0304-4165
e-ISSN
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Volume of the periodical
1820
Issue of the periodical within the volume
10
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
10
Pages from-to
1502-1511
UT code for WoS article
000307369700008
EID of the result in the Scopus database
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