Changes in the intrinsic electrocatalytic nature of Na /K ATPase reflect structural changes on ATP-binding: Electrochemical label-free approach
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F13%3A33143456" target="_blank" >RIV/61989592:15310/13:33143456 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15110/13:33143456
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S1388248112005024" target="_blank" >http://www.sciencedirect.com/science/article/pii/S1388248112005024</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Changes in the intrinsic electrocatalytic nature of Na /K ATPase reflect structural changes on ATP-binding: Electrochemical label-free approach
Original language description
Chronopotentiometric stripping (CPS) analysis was used to show that transmembrane protein Na+/K+-ATPase (NKA) structural changes can be observed in the presence of ATP. The ATP-induced structural changes lead to modulation of NKA ability to catalyze thehydrogen evolution on Hg-electrode. The electrochemical data on NKA are compared to monitoring of changes in intrinsic fluorescence and discussed with respect to crystallographic structures of homologous sarco/endoplasmic reticulum Ca2+-ATPase (SERCA). The results show that CPS analysis of intrinsic electroactivity (label-free approach) could be applied for monitoring of structural changes and molecular interactions of membrane proteins, such as NKA.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CG - Electrochemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Electrochemistry Communications
ISSN
1388-2481
e-ISSN
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Volume of the periodical
27
Issue of the periodical within the volume
FEB
Country of publishing house
US - UNITED STATES
Number of pages
4
Pages from-to
"104?107"
UT code for WoS article
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EID of the result in the Scopus database
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