Magnetically Assisted Surface-Enhanced Raman Scattering Selective Determination of Dopamine in an Artificial Cerebrospinal Fluid and a Mouse Striatum Using Fe3O4/Ag Nanocomposite
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F14%3A33151766" target="_blank" >RIV/61989592:15310/14:33151766 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15110/14:33151766
Result on the web
<a href="http://pubs.acs.org/doi/pdf/10.1021/ac500394g" target="_blank" >http://pubs.acs.org/doi/pdf/10.1021/ac500394g</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/ac500394g" target="_blank" >10.1021/ac500394g</a>
Alternative languages
Result language
angličtina
Original language name
Magnetically Assisted Surface-Enhanced Raman Scattering Selective Determination of Dopamine in an Artificial Cerebrospinal Fluid and a Mouse Striatum Using Fe3O4/Ag Nanocomposite
Original language description
The dopaminergic neural system is a crucial part of the brain responsible for many of its functions including mood, arousal, and other roles. Dopamine is the key neurotransmitter of this system, and a determination of its level presents a demanding taskneeded for a deeper understanding of the processes, even pathological, involving this brain part. In this work, we present a method for a fast analysis of dopamine levels in samples of cerebrospinal fluid and mouse striatum. The method is based on a nanocomposite composed of magnetite and silver nanoparticles, whose surface is modified with iron nitriloacetic acid (Fe-NTA)-a dopamine-selective compound. The magnetic properties of this nanocomposite enable simple separation of targeted molecules from a complex matrix while the silver acts as a platform for surface-enhanced Raman scattering (SERS). Silver and magnetite nanoparticles are joined by carboxymethyl chitosan, useful in biological environments and enhancing the sensitivity due t
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
—
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Analytical Chemistry
ISSN
0003-2700
e-ISSN
—
Volume of the periodical
86
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
2939-2946
UT code for WoS article
000333235700018
EID of the result in the Scopus database
—