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Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F15%3A33155806" target="_blank" >RIV/61989592:15310/15:33155806 - isvavai.cz</a>

  • Alternative codes found

    RIV/00179906:_____/15:10295658

  • Result on the web

    <a href="http://www.sciencedirect.com/science/article/pii/S0928098715001785" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0928098715001785</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.ejps.2015.04.023" target="_blank" >10.1016/j.ejps.2015.04.023</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds

  • Original language description

    A series of novel acridine derivatives has been tested for their ability to inhibit both cancer cell growth and topoisomerase I and II activity. Binding studies of derivatives with calf thymus DNA were also performed.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BO - Biophysics

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    European Journal of Pharmaceutical Sciences

  • ISSN

    0928-0987

  • e-ISSN

  • Volume of the periodical

    2015

  • Issue of the periodical within the volume

    76

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    11

  • Pages from-to

    192-202

  • UT code for WoS article

    000356980300022

  • EID of the result in the Scopus database