Fast separation of selected cathinones and phenylethylamines by supercritical fluid chromatography

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F15%3A33156851" target="_blank" >RIV/61989592:15310/15:33156851 - isvavai.cz</a>
Alternative codes found
RIV/61388971:_____/15:00464011
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S002196731501540X" target="_blank" >http://www.sciencedirect.com/science/article/pii/S002196731501540X</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.chroma.2015.10.061" target="_blank" >10.1016/j.chroma.2015.10.061</a>

Result language
angličtina
Original language name
Fast separation of selected cathinones and phenylethylamines by supercritical fluid chromatography
Original language description
The chromatographic behaviour of eleven synthetic cathinones and four phenylethylamines under supercritical/subcritical fluid conditions was investigated. Four stationary phases with sub-2 mu m particles (Waters Acquity UPC2 BEH silica, BEH 2-ethylpyridine, CSH Fluoro-Phenyl, and HSS C18SB) were evaluated in terms of isomer resolution, chromatographic peak shape, and analysis time. Methanol, water, formic acid, ammonium hydroxide, ammonium acetate, and ammonium formate were mixed with carbon dioxide totest their influence on analyte retention and peak shapes. Methanol and ammonium cations were essential for successful separations. Efficient separations of four isomeric pairs (R > 1), and most of the remaining analytes, were achieved in less than 3.3 min on BEH and Fluoro-Phenyl columns with gradient of methanolic ammonium hydroxide in CO2. Drugs were detected by positive electrospray ionization triple quadrupole mass spectrometry in selected reaction monitoring mode. Added detection s
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
—

Project
<a href="/en/project/LH14064" target="_blank" >LH14064: Analytical tools for fast identification of new designer drugs</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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