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Determination of some hormone antagonists by micellar electrokinetic chromatography

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F15%3A33157134" target="_blank" >RIV/61989592:15310/15:33157134 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Determination of some hormone antagonists by micellar electrokinetic chromatography

  • Original language description

    Contamination of natural waters is a major concern in many parts of the world. Amongst emerging pollutants, Endocrine Disrupting Compounds (EDCs) appear to be particularly prevalent in the aquatic environment, and some aquatic animals are highly susceptible to their effects. Hence, the aim of our study was to develop a simple and fast method for separation and determination of five model hormone antagonists, exemestane, toremifene, letrozole, anastrozole, and mifepristone, by micellar electrokinetic chromatography (MEKC). Within the best conditions, 50 mM sodium borate pH 9.5, 50 mM SDS, 10 % 1-propanol, 20 kV, the separation of all the compounds lasts for 7 minutes. The method was successfully applied for analysis of water samples from a local wastewater treatment plant.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    CB - Analytical chemistry, separation

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/LO1305" target="_blank" >LO1305: Development of the center of advanced technologies and materials</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    CECE 2015 - 12th International Interdisciplinary Meeting on Bioanalysis

  • ISBN

    978-80-904959-3-7

  • ISSN

  • e-ISSN

  • Number of pages

    4

  • Pages from-to

    172-175

  • Publisher name

    Ústav analytické chemie AV ČR, v.v.i.,

  • Place of publication

    Brno

  • Event location

    Brno

  • Event date

    Sep 21, 2015

  • Type of event by nationality

    CST - Celostátní akce

  • UT code for WoS article