15N-labelled pyrazines of triterpenic acids

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F16%3A33160733" target="_blank" >RIV/61989592:15310/16:33160733 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15110/16:33160733 RIV/68407700:21340/16:00232639
Result on the web
<a href="https://link.springer.com/article/10.1007%2Fs10967-015-4479-5" target="_blank" >https://link.springer.com/article/10.1007%2Fs10967-015-4479-5</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10967-015-4479-5" target="_blank" >10.1007/s10967-015-4479-5</a>

Result language
angličtina
Original language name
15N-labelled pyrazines of triterpenic acids
Original language description
Triterpenoid pyrazines from our research group were found selectively cytotoxic on several cancer cell lines with IC50 in low micromolar range. This sparked our interest in preparing their labeled analogs for metabolic studies. In this work, we prepared a set of non-labeled pyrazines from seven triterpenoid skeletal types along with their 15N labelled analogs. In this work, we present the synthesis and characterization of the target 15N labelled pyrazines. Currently, these compounds are being studied in complex metabolic studies.
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)