Enhanced antibacterial effect of antibiotics in combination with silver nanoparticles against animal pathogens

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F16%3A33161260" target="_blank" >RIV/61989592:15310/16:33161260 - isvavai.cz</a>

Result on the web

<a href="http://www.sciencedirect.com/science/article/pii/S1090023315004414" target="_blank" >http://www.sciencedirect.com/science/article/pii/S1090023315004414</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.tvjl.2015.10.032" target="_blank" >10.1016/j.tvjl.2015.10.032</a>

Result language

angličtina

Original language name

Enhanced antibacterial effect of antibiotics in combination with silver nanoparticles against animal pathogens

Original language description

Antibiotic resistant bacteria are a serious health risk in both human and veterinary medicine. Several studies have shown that silver nanoparticles (AgNPs) exert a high level of antibacterial activity against antibiotic resistant strains in humans. The aim of this study was to evaluate the antibacterial effects of a combined therapy of AgNPs and antibiotics against veterinary bacteria that show resistance to antibiotics. A microdilution checkerboard method was used to determine the minimal inhibitory concentrations of both types of antimicrobials, alone and in combination. The fractional inhibitory concentration index was calculated and used to classify observed collective antibacterial activity as synergistic, additive (only the sum of separate effects of drugs), indifferent (no effect) or antagonistic.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Veterinary Journal

ISSN

1090-0233

e-ISSN

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Volume of the periodical

209

Issue of the periodical within the volume

MAR

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

174-179

UT code for WoS article

000371937400027

EID of the result in the Scopus database

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