Does EmbryoGlue transfer medium affect embryo transfer success rate?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F18%3A73606580" target="_blank" >RIV/61989592:15310/18:73606580 - isvavai.cz</a>

Result on the web

<a href="https://www.prolekare.cz/casopisy/ceska-gynekologie/2018-3-12/ovlivnuje-pouziti-transferoveho-media-embryoglue-uspesnost-embryotransferu-105711" target="_blank" >https://www.prolekare.cz/casopisy/ceska-gynekologie/2018-3-12/ovlivnuje-pouziti-transferoveho-media-embryoglue-uspesnost-embryotransferu-105711</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Does EmbryoGlue transfer medium affect embryo transfer success rate?

Original language description

Objective: Verification of the effect of EmbryoGlue (EG) transfer medium enriched with hyaluronan on the embryo transfer success rate. Design: A prospective study. Setting: Fertimed, Fertility Treatment Centre, Olomouc. Methods: 484 patients undergoing IVF + ET were engaged who were divided according to the medium used during transfer: Sage or Vitrolife culture medium (n = 135) and EG transfer medium (n = 349). The influence of other factors was also evaluated: age, number of received oocytes, percentage of fertilised oocytes, endometrium height on the day of transfer, number of preserved embryos, number of transferred embryos and the length of cultivation (48, 72, 96, 120 h). These factors were considered quantitative variables while the method of hormone stimulation, the type of culture medium and the application of EG were considered qualitative (categorical) variables. Results: With the use of EG the chances of conception increased by approximately 9%. The negative effect of higher age on implantation proportion and the positive effect of cultivation prolongation were proven. The effect of EG on miscarriages was not proven. The probability of miscarriage diminished with higher oocyte fertilisation. The culture medium used (Sage or Vitrolife) before the application of EG does not affect the gravidity result. Conclusion: Using the transfer medium of EmbryoGlue before embryo transfer affects the pregnancy rate (PR) in a positive manner. The influence on pregnancy loss with the application of EG was not proven.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

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OECD FORD branch

10604 - Reproductive biology (medical aspects to be 3)

Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Ceska Gynekologie-Czech Gynaecology

ISSN

1210-7832

e-ISSN

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Volume of the periodical

83

Issue of the periodical within the volume

3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

5

Pages from-to

177-181

UT code for WoS article

000458872400003

EID of the result in the Scopus database

2-s2.0-85056076920