Cytokinin Signalling and Mechanism of Action of Meta-Topolin and Its Derivatives
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F21%3A73610643" target="_blank" >RIV/61989592:15310/21:73610643 - isvavai.cz</a>
Result on the web
<a href="https://obd.upol.cz/id_publ/333190530" target="_blank" >https://obd.upol.cz/id_publ/333190530</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-981-15-9046-7_5" target="_blank" >10.1007/978-981-15-9046-7_5</a>
Alternative languages
Result language
angličtina
Original language name
Cytokinin Signalling and Mechanism of Action of Meta-Topolin and Its Derivatives
Original language description
The discovery of ortho-topolin, meta-topolin and its conjugates in the early 1990s prompted further research on the biological activity of these aromatic cytokinins. Structure–activity relationship studies (SAR) revealed that hydroxylation at the meta-position on the benzyl side chain of BAP and its riboside significantly improved the compound performance in standardized cytokinin bioassays compared to BAP. Elucidation of the molecular mechanism of the cytokinin signal transduction and identification of membrane-bound receptor histidine kinase (HK) led to deeper understanding of the function of topolins in planta. While aromatic cytokinins generally show weak interaction with Arabidopsis and other cytokinin-sensitive HKs, meta-topolin is able to provoke a strong response comparable to that observed with the most active isoprenoid free bases. In contrast, ortho-topolin and para-topolin are much less active, and it is possible that hydroxylation at these positions serves as a deactivation step. In contrast, derivatives of meta-topolin, although not directly interacting with cytokinin-sensitive HKs, have proven to be very useful in plant propagation techniques, and slow gradual release of the free active base allows for the potentiation of cytokinin effects. This chapter summarizes basic facts about cytokinin signalling and adds to our knowledge of signalling aspects and metabolism of aromatic cytokinins in various plant models.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
10611 - Plant sciences, botany
Result continuities
Project
<a href="/en/project/EF17_048%2F0007323" target="_blank" >EF17_048/0007323: Development of pre-applied research in nanotechnogy and biotechnology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Meta-topolin: A Growth Regulator for Plant Biotechnology and Agriculture
ISBN
978-981-15-9045-0
Number of pages of the result
10
Pages from-to
39-48
Number of pages of the book
339
Publisher name
Springer
Place of publication
Singapore
UT code for WoS chapter
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