A Study on the Chemistry and Biological Activity of 26-Sulfur Analogs of Diosgenin: Synthesis of 26-Thiodiosgenin S-Mono- and Dioxides, and Their Alkyl Derivatives

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F22%3A73616114" target="_blank" >RIV/61989592:15310/22:73616114 - isvavai.cz</a>

Result on the web

<a href="https://www.mdpi.com/1420-3049/28/1/189" target="_blank" >https://www.mdpi.com/1420-3049/28/1/189</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/molecules28010189" target="_blank" >10.3390/molecules28010189</a>

Result language

angličtina

Original language name

A Study on the Chemistry and Biological Activity of 26-Sulfur Analogs of Diosgenin: Synthesis of 26-Thiodiosgenin S-Mono- and Dioxides, and Their Alkyl Derivatives

Original language description

A chemoselective procedure for MCPBA oxidation of 26-thiodiosgenin to corresponding sulfoxides and sulfone was elaborated. An unusual equilibration of sulfoxides in solution was observed. Moreover, alpha-alkylation of sulfoxide and sulfone was investigated. Finally, the biological activity of obtained compounds was examined.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10401 - Organic chemistry

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

MOLECULES

ISSN

1420-3049

e-ISSN

1420-3049

Volume of the periodical

28

Issue of the periodical within the volume

1

Country of publishing house

CH - SWITZERLAND

Number of pages

18

Pages from-to

"189-1"-"189-18"

UT code for WoS article

000909222400001

EID of the result in the Scopus database

2-s2.0-85145729760