Dietary monoterpenoids and human health: Unlocking the potential for therapeutic use
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F25%3A73626967" target="_blank" >RIV/61989592:15310/25:73626967 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0300908424002025" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0300908424002025</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.biochi.2024.09.002" target="_blank" >10.1016/j.biochi.2024.09.002</a>
Alternative languages
Result language
angličtina
Original language name
Dietary monoterpenoids and human health: Unlocking the potential for therapeutic use
Original language description
Natural products are widely used in different aspects of our lives – from household cleaners and food production, via cosmetics and aromatherapy, to both alternative and traditional medicine. In our research group, we have recently described several monoterpenoids with potential in the antiviral and anticancer therapy by allosteric targeting of aryl hydrocarbon receptor (AhR). Prior to any practical application, biological effects on human organism must be taken in concern. This review article is focused on the biological effects of 5 monoterpenoids on the human health previously identified as AhR antagonists with a therapeutic potential as antiviral and anticancer agents. We have thoroughly described cytotoxic, anti-inflammatory, anti-proliferative, and anticancer effects, as well as known interactions with nuclear receptors. As clearly demonstrated, monoterpenoids in general represent almost an inexhaustible reservoir of natural compounds possessing the ability to influence, modulate and improve human health.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
<a href="/en/project/GA23-04662S" target="_blank" >GA23-04662S: Dietary monoterpenoids as a novel class of aryl hydrocarbon receptor negative allosteric modulators in the therapy of colon cancer</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BIOCHIMIE
ISSN
0300-9084
e-ISSN
1638-6183
Volume of the periodical
228
Issue of the periodical within the volume
JAN
Country of publishing house
FR - FRANCE
Number of pages
12
Pages from-to
89-100
UT code for WoS article
001401359600001
EID of the result in the Scopus database
2-s2.0-85204397465