Engineered protein-iron and/or gold-protein-iron nanocomposites in aqueous solutions upon UVA light: Photo-induced electron transfer possibilities and limitations

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15640%2F24%3A73624553" target="_blank" >RIV/61989592:15640/24:73624553 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15310/24:73624553

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S1010603023008808?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1010603023008808?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jphotochem.2023.115415" target="_blank" >10.1016/j.jphotochem.2023.115415</a>

Result language

angličtina

Original language name

Engineered protein-iron and/or gold-protein-iron nanocomposites in aqueous solutions upon UVA light: Photo-induced electron transfer possibilities and limitations

Original language description

Occurrence/suppression of photo-induced electron transfer (PI -ET) process in solutions of nanocomposites represents a very hot topic in several photo-related research domains. In this work, this phenomenon is investigated in aqueous solutions using iron-containing mono-/bi-metallic nanocomposites that have been engineered through protein-templated syntheses, with the aim to potentially create new biocompatible imaging contrast agents for medical diagnostics. Two types of iron-containing nanocomposites, mono-metallic (protein -Fe) and bimetallic (Au -protein -Fe), have been synthesized and characterized with the aid of several experimental techniques, such as high-resolution transmission electron microscopy (HR -TEM), steady -state fluorescence, electron paramagnetic resonance (EPR) and light-induced EPR (LEPR). Theoretical model of the N -terminal region of the bovine serum albumin protein interacting with Fe cations and simulations of the EPR spectral features upon UVA light irradiation complemented the material&apos;s analysis. Two iron forms within the mono-/bi-metallic nanocomposites have been detected experimentally: (i) complexed iron cations (giving EPR signal at g = 4.29) and (ii) superparamagnetic iron oxide nanoparticles (SPIONs; expressing EPR resonances at g// = 2.21 and g perpendicular to = 2.09). Upon UVA-light irradiation (325 nm), PI -ET between the two iron forms have been observed in the protein -Fe nanocomposite; however, this electronic communication is suppressed in the Au -protein -Fe system. The presence of luminescent Au nanoclusters and dissimilar sizes of SPIONs in bi-metallic nanocomposites (around 5 nm vs. approx. 2 nm in the monometallic protein -Fe system) represent the two possible reasons underneath suppression of the PI -ET process in the former. Moreover, center dot OH radicals were detected in aqueous solutions in both iron-containing nanocomposites (Fe and Au/Fe systems) when irradiated at 325 nm for 5 min at r. t. The reported evidence of PI -ET in iron-containing nanocomposite aqueous solutions can thus have a large impact on their potential medical and/or environmental applications.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10403 - Physical chemistry

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY

ISSN

1010-6030

e-ISSN

1873-2666

Volume of the periodical

450

Issue of the periodical within the volume

May

Country of publishing house

CH - SWITZERLAND

Number of pages

13

Pages from-to

nestránkováno

UT code for WoS article

001155889100001

EID of the result in the Scopus database

2-s2.0-85181754721