Phytochelatin modified electrode surface as a sensitive heavy-metal ion biosensor

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F05%3A00000172" target="_blank" >RIV/62156489:43210/05:00000172 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Phytochelatin modified electrode surface as a sensitive heavy-metal ion biosensor

Original language description

Electrochemical biosensors have superior properties over other existing measurement systems because they can provide rapid, simple and low-cost on-field determination of many biological active species and a number of dangerous pollutants. In our work, wesuggested a new heavy metal biosensor based on interaction of heavy metal ions ( Cd2+ and Zn2+) with phytochelatin, which was adsorbed on the surface of the hanging mercury drop electrode, using adsorptive transfer stripping differential pulse voltammetry. In addition, we applied the suggested technique for the determination of heavy metals in a biological sample - human urine and platinum in a pharmaceutical drug. The detection limits ( 3 S/N) of Cd(II), Zn(II) and cis-platin were about 1.0, 13.3 and1.9 pmole in 5 mu l, respectively. On the basis of the obtained results, we propose that the suggested technique offers simple, rapid, and low-cost detection of heavy metals in environmental, biological and medical samples.

Czech name

Fytochelatiny modifikovaný povrch elektrody jako senzitivní biosenzor pro detekci těžkých kovů

Czech description

Electrochemical biosensors have superior properties over other existing measurement systems because they can provide rapid, simple and low-cost on-field determination of many biological active species and a number of dangerous pollutants. In our work, wesuggested a new heavy metal biosensor based on interaction of heavy metal ions ( Cd2+ and Zn2+) with phytochelatin, which was adsorbed on the surface of the hanging mercury drop electrode, using adsorptive transfer stripping differential pulse voltammetry. In addition, we applied the suggested technique for the determination of heavy metals in a biological sample - human urine and platinum in a pharmaceutical drug. The detection limits ( 3 S/N) of Cd(II), Zn(II) and cis-platin were about 1.0, 13.3 and1.9 pmole in 5 mu l, respectively. On the basis of the obtained results, we propose that the suggested technique offers simple, rapid, and low-cost detection of heavy metals in environmental, biological and medical samples.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CG - Electrochemistry

OECD FORD branch

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Project

<a href="/en/project/GP525%2F04%2FP132" target="_blank" >GP525/04/P132: Study of protection mechanisms for stress-induced by heavy metals</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2005

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Sensors

ISSN

1424-8220

e-ISSN

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Volume of the periodical

5

Issue of the periodical within the volume

1-2

Country of publishing house

CH - SWITZERLAND

Number of pages

15

Pages from-to

70-84

UT code for WoS article

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EID of the result in the Scopus database

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