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The role of neutrophil apoptosis during experimentally induced Streptococcus uberis mastitis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F06%3A00095107" target="_blank" >RIV/62156489:43210/06:00095107 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The role of neutrophil apoptosis during experimentally induced Streptococcus uberis mastitis

  • Original language description

    The object of the study was to determine if apoptosis of neutrophils and their subsequent elimination from the mammary gland by macrophages are modulated by an infection of Streptococcus uberis. After PBS and S. uberis administration the total number ofboth Annexin V+/PI- neutrophils and karyopycnotic neutrophils peaked at 24 hours. The highest percentages of Annexin V+/PI- neutrophils were detected at 72 hours after PBS and S. uberis, respectively. The highest percentages of karyopycnotic neutrophilswere detected at 72 hours after PBS and 168 hours after S. uberis, respectively. The total number of MPO+ macrophages was the highest at 24 hour after PBS and 72 hours after S. uberis. The percentage of MPO+ macrophages was the highest at 72 hours afterPBS and S. uberis. The results of this study demonstrate that during experimental infection of the mammary gland by S. uberis, the apoptosis of neutrophils is modulated.

  • Czech name

    Role apoptózy neutrofilních granulocytů během experimentální infekce mléčné žlázy Streptococcus uberis

  • Czech description

    Předmětem bylo zjištění, zda apoptóza neutrofilů a jejich eliminace makrofágy jsou modulovány infekcí Streptococcus uberis. 24 h po intramammární aplikaci PBS a S. uberis došlo ke zvýšení počtu Annexin V+/PI- a karyopyknotických neutrofilů. Nejvyšší procentuální zastoupení těchto buněk bylo detekováno 72h po PBS a S. uberis. Nejvyšší procento karyopyknotických neutrofilů bylo detekováno 72h po PBS a 168 h po S. uberis. Celkový počet myeloperoxidáza pozitivních makrofágů byl nejvyšší 24 h po PBS a 72 h po S. uberis. Procentické zastoupení těchto buněk bylo nejvyšší 72 h po PBS a zároveň u S. uberis. Výsledky této studie demonstrují, že experimentální infekce mléčné žlázy skotu S. uberis moduluje apoptózu neutrofilních granulocytů.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    GJ - Diseases and animal vermin, veterinary medicine

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA524%2F03%2F1531" target="_blank" >GA524/03/1531: The role of mononuclear phagocytes during the acute inflammation of the bovine mammary gland</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Veterinary Medicine Czech

  • ISSN

    0375-8427

  • e-ISSN

  • Volume of the periodical

  • Issue of the periodical within the volume

    51

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    13

  • Pages from-to

    265-277

  • UT code for WoS article

  • EID of the result in the Scopus database