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Maize beta-glucosidase Zm-60.1 and its mutant forms: Optimization of purification procedure

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F07%3A00117765" target="_blank" >RIV/62156489:43210/07:00117765 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Maize beta-glucosidase Zm-60.1 and its mutant forms: Optimization of purification procedure

  • Original language description

    beta-Glucosidases serve different roles in planta and indeed we find that plants have several different groups of this enzyme. Some of them can release active zeatin from zeatin-O-glucoside, a cytokinin conjugate thought to be the transport or storage form. One such enzyme is Zm-p60.1 from Zea mays. We have over-expressed the cDNA encoding Zm-p60.1 in E. coli and subsequently purified the recombinant protein using a purification procedure (Zouhar et al., 1999, Verdoucq et al., 2003) which uses a phosphate buffer system, imidazole as eluent. This procedure has been successfully applied to purify the native protein, but attempts to purify His-tagged mutants were not successful. The presence of glycerol (a protection agent) in the elution solutions causesprecipitation of some mutants, and protein denaturation occurred during hydrophobic column chromatography. We therefore had to completely revise the purification protocol. For purification of recombinant enzyme and its histidine mutant f

  • Czech name

    Kukuřičná beta-glukosidasa Zm-p60.1 a jejích mutantních forem: Optimalisace purifikační procedury

  • Czech description

    Práce řeší vylepšení purifikační rutiny isolace a purifikace rekombinantní kukuřičné beta-glukosidasy Zm-p60.1.

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/LC06034" target="_blank" >LC06034: Regulation of morphogenesis of plant cells and organs</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    MendelNet'07 Agro

  • ISBN

    978-80-7375-119-7

  • ISSN

  • e-ISSN

  • Number of pages

    1

  • Pages from-to

    103-103

  • Publisher name

    MZLU v Brno

  • Place of publication

  • Event location

    Brno

  • Event date

    Jan 1, 2007

  • Type of event by nationality

    CST - Celostátní akce

  • UT code for WoS article