Biochemical profile of effect of deoxynivalenol supplemented by mouldy cereals on rats

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F10%3A00166775" target="_blank" >RIV/62156489:43210/10:00166775 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Biochemical profile of effect of deoxynivalenol supplemented by mouldy cereals on rats
Original language description
The aims of this thesis consisted of investigating the impact mouldy grain contaminated with deoxynivalenol (DON) on the health status of rats and their ability to resist oxidative stress. Rats were 28 days feeding of diet supplemented with DON and others (organic and inorganic zinc, the addition of vitamins and mycosorb). Among the factors determining the levels of defences include peptides and proteins (glutathione, metallothionein (MT)). The highest concentration of MT was found in the tissues providing detoxification of xenobiotics, such as kidney (6.69 +/- 0.05 microg/ml) and liver (6.06 +/- 0.05 microg/ml). Half concentration was detected in heart, brain, testes and muscle (app. 3.0 microg/ml). In conclusion, the MT may play an important role inthe detoxification of mycotoxins. Its role is not fully understood, but this protein is most likely associated with the redistribution of ions important for transcription factors and its interaction with reactive oxygen species that can f
Czech name
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Czech description
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Project
<a href="/en/project/GP301%2F09%2FP436" target="_blank" >GP301/09/P436: Metallothionein analysis in prostate carcinoma at DNA, RNA and protein level.</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
MendelNet 2010 Proceedings of International Ph.D. Students Conference
ISBN
978-80-7375-453-2
ISSN
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e-ISSN
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Number of pages
7
Pages from-to
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Publisher name
Mendelova univerzita v Brně, Agronomická fakulta
Place of publication
Brno
Event location
Brno
Event date
Jan 1, 2000
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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