Determination of metallothionein, glutathione and termostable protein fraction concentrations in tumour tissue from head and neck area

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F10%3A00184598" target="_blank" >RIV/62156489:43210/10:00184598 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Determination of metallothionein, glutathione and termostable protein fraction concentrations in tumour tissue from head and neck area

Original language description

Tumours of head and neck are one of the most incident tumour diseases. Well-timed diagnosis plays main role in their therapy. Aim of this work consisted in determination of metallothionein (MT), which could be new tumour marker. Determination of its concentration was carried out using electrochemical detection with use of differential pulse voltammetry. Concentrations of MT in samples of denaturized blood plasma of group of patients were about 2.3 uM with slight differences in accordance with localization of tumours. Contents of glutathione and total proteins in denaturized were determined chromatographically and by the help of Biuret reaction. Rate of concentrations levels of GSH/GSSG was varying from 1.31 to 17.66.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Biochemical Technology

ISSN

0974-2328

e-ISSN

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Volume of the periodical

2

Issue of the periodical within the volume

5

Country of publishing house

IN - INDIA

Number of pages

2

Pages from-to

29-30

UT code for WoS article

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EID of the result in the Scopus database

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