Cell Signals as Markers of Cytotoxicity of New Complexes of Naphthoquinones

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F10%3A00185836" target="_blank" >RIV/62156489:43210/10:00185836 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Cell Signals as Markers of Cytotoxicity of New Complexes of Naphthoquinones

Original language description

Naphthoquinones as group of secondary metabolites of plants demonstrate very interesting pharmacological properties, which are based on different mechanisms, especially on ability of interaction with DNA and generation of reactive oxygen species. Complexes of naphthoquinones with heavy metal can enhance these properties, especially cytotoxic. Due to this fact, we were focused on characterization of complex of naphthoquinone lawsone with copper(II) ions. This newly synthesized complex demonstrated significant cytotoxic, respectively phytotoxic properties.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biosignál

ISSN

1211-412X

e-ISSN

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Volume of the periodical

1

Issue of the periodical within the volume

6

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

5

Pages from-to

259-263

UT code for WoS article

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EID of the result in the Scopus database

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