Elektrochemické analýze DNA a interakce iontů kadmia

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F11%3A00174061" target="_blank" >RIV/62156489:43210/11:00174061 - isvavai.cz</a>

Alternative codes found

RIV/00216305:26220/11:PU99190

Result on the web

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DOI - Digital Object Identifier

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Result language

čeština

Original language name

Electrochemical analysis of DNA and cadmium ions interaction

Original language description

Cadmium (Cd) is a highly toxic environmental pollutant dangerous especially due to the ability of accumulation. Cd is emitted to the environment mostly by metallurgy, mining industry and production of nickel-cadmium batteries. The intoxication is causedmostly by cigarette smoke, foodstuffs and air pollution. The connection between cadmium and prostate, lung and testicles cancer as well as kidney and liver failure, lung oedema and spondylomalacia was proven. (Tokumoto 2011). Cd also generates reactive oxygen forms, damage DNA influence the function of proteins connected with an antioxidant defence of the organism. This work is focused on monitoring of the interactions between Cd ions and chicken genome DNA by square wave voltammetry on hanging mercurydrop electrode. Significant signal decrease of 25% and 80% was observed in DNA exposed to Cd ions for 1 hour and 3 days, respectively.

Czech name

Electrochemical analysis of DNA and cadmium ions interaction

Czech description

Cadmium (Cd) is a highly toxic environmental pollutant dangerous especially due to the ability of accumulation. Cd is emitted to the environment mostly by metallurgy, mining industry and production of nickel-cadmium batteries. The intoxication is causedmostly by cigarette smoke, foodstuffs and air pollution. The connection between cadmium and prostate, lung and testicles cancer as well as kidney and liver failure, lung oedema and spondylomalacia was proven. (Tokumoto 2011). Cd also generates reactive oxygen forms, damage DNA influence the function of proteins connected with an antioxidant defence of the organism. This work is focused on monitoring of the interactions between Cd ions and chicken genome DNA by square wave voltammetry on hanging mercurydrop electrode. Significant signal decrease of 25% and 80% was observed in DNA exposed to Cd ions for 1 hour and 3 days, respectively.

Type

D - Article in proceedings

CEP classification

CG - Electrochemistry

OECD FORD branch

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Project

<a href="/en/project/GA102%2F08%2F1546" target="_blank" >GA102/08/1546: Miniaturized intelligent systems and nanostructured elektrodes for chemical, biological, and pharmaceutical applications (NANIMEL)</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

XI. pracovní setkání fyzikálních chemiků a elektrochemiků

ISBN

978-80-7375-514-0

ISSN

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e-ISSN

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Number of pages

4

Pages from-to

144-147

Publisher name

Mendelova univerzita v Brně

Place of publication

Brno

Event location

MENDELU

Event date

Jan 1, 2011

Type of event by nationality

CST - Celostátní akce

UT code for WoS article

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