Metallothionein based biosensor for determination of heavy metals

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F11%3A00183666" target="_blank" >RIV/62156489:43210/11:00183666 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Metallothionein based biosensor for determination of heavy metals
Original language description
Occurrence of heavy metals in the environment and their entry into the food chain, with all their negative properties is an ongoing problem. The most important role in solving this problem plays rapid and easy-to-use systems for detection of heavy metalsin environment (Cd, Pb, As, Hg). Metallothionein is an intracellular protein which has been known since 1957, and which has very good affinity for heavy metal ions. In its structure up to seven of divalent metal ions can be bound. We attempted to use this feature for designing of our biosensor. Recently there is a greater demand for biosensors where the detection feature is provided via bacteria, peptides, proteins or nucleic acids. The resulting biosensors are characterized by a high specificity and low detection limits. In addition to these properties (the biosensor can be modified to be applicable in situ) but with similar or almost similar results as laboratory measurements. The main objective of this study is to design a biosensor
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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