Caveolin-1 as a potential high-risk prostate cancer biomarker

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F12%3A00182847" target="_blank" >RIV/62156489:43210/12:00182847 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/12:8050 RIV/00216305:26620/12:PU97493 RIV/00064203:_____/12:8050 RIV/00216224:14110/12:00064830

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Caveolin-1 as a potential high-risk prostate cancer biomarker

Original language description

Current diagnostic techniques of prostate cancer cannot efficiently distinguish the latent and low-risk forms from the high-risk significant forms of prostate cancer. Caveolin-1 (Cav-1), except other functions, plays an important role in cell transformation and the process of tumorigenesis. Furthermore, Cav-1 is involved in metastatic processes. It has also been shown that Cav-1 expression is induced under stress conditions, such as oxidative stress. The present study focused on the determination of prognostic markers of aggressive (high-grade) forms of prostate cancer. We determined serum Cav-1 and serum markers of antioxidant activity-glutathione (GSH), 2,2-diphenyl-1-picrylhydrazyl (DPPH), Trolox equivalent antioxidant capacity (TEAC), ferric-reducing antioxidant power (FRAP), N,N-dimethyl-1,4-diaminobenzene (DMPD), free radicals method (FRK) and blue chromium peroxide (Cro) in 97 serum samples (82 prostate cancer patients and 15 controls). We found insignificant differences in Cav-

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

—

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Oncology Reports

ISSN

1021-335X

e-ISSN

—

Volume of the periodical

27

Issue of the periodical within the volume

3

Country of publishing house

GR - GREECE

Number of pages

11

Pages from-to

831-841

UT code for WoS article

—

EID of the result in the Scopus database

—