Effect of Missense Mutation of Leptin Gene on Serum Leptin Concentration and Some Blood Metabolic Parameters in Czech Pied Bulls

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F13%3A00213249" target="_blank" >RIV/62156489:43210/13:00213249 - isvavai.cz</a>

Alternative codes found

RIV/49608851:_____/13:#0000588

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Effect of Missense Mutation of Leptin Gene on Serum Leptin Concentration and Some Blood Metabolic Parameters in Czech Pied Bulls

Original language description

The aim of present study was to examine the effect of leptin gene single nucleotide polymorphism (C/T) giving missense mutation (Arg25Cys) on concentration of some serum metabolic parameters in 58 Czech Pied bulls. Resulting genotypes in the exon 2 wereCC (48.3%), CT (36.2%), and TT (15.5%). There were no differences in serum leptin, thyroxin (T4), triiodothyronin (T3), glucose, triacylglycerols and non-esterified fatty acid concentrations among the genotypes. However, concentration of serum insulin inbulls with TT genotype was significantly higher than those of TC and CC genotypes. Since it is shown that the T allele is associated with the trait of higher fat contents, higher insulin concentration in TT genotype might contribute to accumulation of triacylglycerols in the adipose tissue.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

ED - Physiology

OECD FORD branch

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Project

<a href="/en/project/QI91A055" target="_blank" >QI91A055: The assessment of association among the genotype for leptin, leptin concentration in blood and meat quality characteristics to use it for Czech Fleckvieh cattle breeding.</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Bulgarian Journal of Agricultural Science

ISSN

1310-0351

e-ISSN

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Volume of the periodical

19

Issue of the periodical within the volume

6

Country of publishing house

BG - BULGARIA

Number of pages

6

Pages from-to

1425-1430

UT code for WoS article

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EID of the result in the Scopus database

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