Study of interaction between metallothionein and CdTe quantum dots

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F13%3A00213473" target="_blank" >RIV/62156489:43210/13:00213473 - isvavai.cz</a>

Alternative codes found

RIV/60461373:22330/13:43895529 RIV/00216305:26620/13:PU126542

Result on the web

<a href="http://dx.doi.org/10.1007/s10337-013-2418-6" target="_blank" >http://dx.doi.org/10.1007/s10337-013-2418-6</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10337-013-2418-6" target="_blank" >10.1007/s10337-013-2418-6</a>

Result language

angličtina

Original language name

Study of interaction between metallothionein and CdTe quantum dots

Original language description

Quantum dots (QDs) belong to a new class of fluorescent agent for biochemical, medicinal or other purposes. However, QDs based on cadmium or other metals can be risky for an organism. As one of the mechanism how to detoxify cadmium-based QDs expression of metallothioneins (MT) can be considered. Due to high affinity of metallothionein to cadmium(II) ions, we attempted to develop an approach for studying of possible interaction with QDs. We prepared QDs with CdTe core and studied the interaction with MT,which we isolated from livers of Cd-administered rabbits. To study the interaction, we used the mixture of both components MT (3.6 uM): CdTe QDs (0, 0.34, 0.68, 1.02, 1.36, 1.7, 2.04 and 2.47 uM). The mixtures were studied by spectrophotometry within the range from 200 to 750 nm with detected maxima at 260 and 505 nm. Same mixtures were also analysed by differential pulse voltammetry Brdicka reaction, which supported data from spectrophotometry. Subsequently, we used fast protein liquid

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chromatographia

ISSN

0009-5893

e-ISSN

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Volume of the periodical

76

Issue of the periodical within the volume

7-8

Country of publishing house

DE - GERMANY

Number of pages

9

Pages from-to

345-353

UT code for WoS article

316819600007

EID of the result in the Scopus database

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