Porcine ubiquitin-like 5 (UBL5) gene: genomic organization, polymorphisms, mRNA cloning, splicing variants and association study

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F14%3A00215776" target="_blank" >RIV/62156489:43210/14:00215776 - isvavai.cz</a>
Alternative codes found
RIV/67985904:_____/14:00427358
Result on the web
<a href="http://link.springer.com/article/10.1007%2Fs11033-014-3089-6" target="_blank" >http://link.springer.com/article/10.1007%2Fs11033-014-3089-6</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s11033-014-3089-6" target="_blank" >10.1007/s11033-014-3089-6</a>

Result language
angličtina
Original language name
Porcine ubiquitin-like 5 (UBL5) gene: genomic organization, polymorphisms, mRNA cloning, splicing variants and association study
Original language description
Ubiquitin-like 5 (UBL5), which is supposed to be involved in regulation of feed intake, energy metabolism, obesity and type 2 diabetes, is located at position 62.1 cM on the pig chromosome 2 region harbouring quantitative trait loci for carcass and meatquality. The 4,354 bp genomic sequence (FR798948) of the porcine gene encompassing the promoter and entire gene was cloned by polymerase chain reaction. Comparative sequencing revealed 13 polymorphisms in noncoding regions. Synthesis of full-length cDNAsequences using rapid amplification of 50 and 30 ends showed three splice variants. Variants 1 and 2 differ in transcription length for the untranslated part of exon 1 with deduced protein of 73 amino acid (aa) residues and 100 % identities between human, mouse and other species. Variant 3, with 4 bp deletion at the 30 end of exon 2, encodes a truncated protein with 28 aa residues. In a Wild boar9Meishan F2 population (n = 334) with 47 recorded traits, loci FR798948:g.2788G[A and FR79894
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
GI - Farm animal breeding and farm animal pedigree breeding
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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