Y-Fe2O3 magnetic core functionalized with tetraethyl orthosilicate and 3-aminopropyl triethoxysilane for an isolation of H7N7 influenza serotype virions

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F14%3A00230305" target="_blank" >RIV/62156489:43210/14:00230305 - isvavai.cz</a>
Result on the web
<a href="http://www.electrochemsci.org/papers/vol9/90703374.pdf" target="_blank" >http://www.electrochemsci.org/papers/vol9/90703374.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Y-Fe2O3 magnetic core functionalized with tetraethyl orthosilicate and 3-aminopropyl triethoxysilane for an isolation of H7N7 influenza serotype virions
Original language description
The influenza viruses cause annual epidemics of respiratory disease and occasional pandemics, which constitute a major public-health issue. The most important tool in the diagnosis of influenza pandemic is timely and right diagnosis. Hence, this study presents synthesis of paramagnetic particles formed by nanomaghemite (Y-Fe2O3) core, whose surface was functionalized with tetraethyl orthosilicate (TEOS) and 3-aminopropyl triethoxysilane (APTES), able to bind H7N7 influenza virions. Paramagnetic particles show the ability to immobilize virions for direct analysis using ion-exchange chromatography with VIS detection. The presence of H7N7 virions on surface of paramagnetic beads was confirmed by matrix-assisted laser desorption/ionization time of flight mass spectrometry, based upon the mass weight of H7N7 virions, determined before and after establishment of binding. Moreover, using scanning electrochemical microscopy revealed, that binding is provided due to strong charge-charge interac
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
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Project
<a href="/en/project/QJ1230066" target="_blank" >QJ1230066: Effect of soil degradation on complex soil properties including conservation measures for restoration soil agroecological function</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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