Optimization of the Glutathione Detection by High Performance Liquid Chromatography with Electrochemical Detection in the Brain and Liver of Rats Fed with Taurine

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F15%3A43906310" target="_blank" >RIV/62156489:43210/15:43906310 - isvavai.cz</a>

Alternative codes found

RIV/62156489:43410/15:43906310 RIV/00216305:26220/14:PU116443

Result on the web

<a href="http://www.electrochemsci.org/papers/vol10/100201716.pdf" target="_blank" >http://www.electrochemsci.org/papers/vol10/100201716.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Optimization of the Glutathione Detection by High Performance Liquid Chromatography with Electrochemical Detection in the Brain and Liver of Rats Fed with Taurine

Original language description

Taurine exhibits many positive effects on organism, such as induction of important protective biochemical mechanisms and antioxidant effects. In this work, we studied the effect of taurine consumption on levels of taurine, reduced glutathione (GSH) and metallothionein in liver and brain tissues of Wistar rats. The aim of the experiment was the monitoring of changes in concentration of taurine in brain and liver tissues and also changes in concentration of GSH and metallothionein. After optimization, thelimit of detection of GSH in brain and liver tissue was established as 40 nmol.g(-1) of protein and 90 nmol.g(-1) of protein, respectively. That is sufficient for determination of the concentration alterations of GSH in studied tissues. The consumptionof taurine increased content of GSH determined in the brain and liver (increased by approximately 0.8 mmol.g(-1) of protein in comparison with control). The increase of concentration of taurine occurred only in the brain, by cca 50 mu g.g

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

GH - Nutrition of farm animals

OECD FORD branch

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Project

<a href="/en/project/ED2.1.00%2F03.0072" target="_blank" >ED2.1.00/03.0072: Centre of sensor, information and communication systems</a><br>

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal of Electrochemical Science

ISSN

1452-3981

e-ISSN

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Volume of the periodical

10

Issue of the periodical within the volume

2

Country of publishing house

CS - SERBIA AND MONTENEGRO

Number of pages

12

Pages from-to

1716-1727

UT code for WoS article

000348365800054

EID of the result in the Scopus database

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