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Effects of probiotic on morphological changes in porcine macrophages during in vitro cultivation

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F15%3A43906908" target="_blank" >RIV/62156489:43210/15:43906908 - isvavai.cz</a>

  • Result on the web

    <a href="https://mnet.mendelu.cz/mendelnet2015/articles/64_sustrova_1196.pdf" target="_blank" >https://mnet.mendelu.cz/mendelnet2015/articles/64_sustrova_1196.pdf</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Effects of probiotic on morphological changes in porcine macrophages during in vitro cultivation

  • Original language description

    Nowadays, Bifidobacterium bifidum, Lactobacillus rhamnosus and Enterococcus faecium are frequently used probiotics in porcine nutrition. The probiotics-immunobiotics positively influence function of gastrointestinal tract and can also modulate function of immune system. The probiotics interact with immune cells as macrophages, neutrophils, dendritic cells or other immune cells and stimulate them to produce cytokines or to enhance phagocytosis. The aim of this study was to determine whether interactionsof probiotics with porcine monocyte derived macrophages (MDMF) lead to structural changes of these cells during in vitro cultivation. We used the light microscopy and our findings suggest that probiotics affected the structural changes of porcine MDMF. Part of MDMF underwent apoptosis or necrosis and it was described the different stadia leading to the cell death. In some MDMF numerous vacuoles are accumulated in cytoplasm. The most pronounced structural changes of MDMF were caused by En

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    GJ - Diseases and animal vermin, veterinary medicine

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    MendelNet 2015: Proceedings of International PhD Students Conference

  • ISBN

    978-80-7509-363-9

  • ISSN

  • e-ISSN

  • Number of pages

    5

  • Pages from-to

    489-493

  • Publisher name

    Mendelova univerzita v Brně

  • Place of publication

    Brno

  • Event location

    Brno

  • Event date

    Nov 11, 2015

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article

    000366466100093