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Elucidating protein posttranslational modifications using combination of recombinant protein spectral library and in silico designed SRM analysis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F15%3A43906942" target="_blank" >RIV/62156489:43210/15:43906942 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Elucidating protein posttranslational modifications using combination of recombinant protein spectral library and in silico designed SRM analysis

  • Original language description

    Posttranslational modifications (PTMs) of proteins represent fascinating extensions of the dynamic complexity of proteomes of living cells, but also present a difficult obstacle in the proteome analysis. Identification and mapping of PTMs in proteins have improved dramatically, but to comprehend complex mechanisms and biological functions, one must address also very low abundant proteins. Here, we demonstrate in silico derived analysis of a low abundant target of ubiquitination and the MS/MS identification of the predicted ubiquitination sites.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    MendelNet 2015: Proceedings of International PhD Students Conference

  • ISBN

    978-80-7509-363-9

  • ISSN

  • e-ISSN

  • Number of pages

    3

  • Pages from-to

    409-411

  • Publisher name

    Mendelova univerzita v Brně

  • Place of publication

    Brno

  • Event location

    Brno

  • Event date

    Nov 11, 2015

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article

    000366466100075