All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Melatonin Regulates Oxidative Stress Initiated by Freund's Complete Adjuvant

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F15%3A43907744" target="_blank" >RIV/62156489:43210/15:43907744 - isvavai.cz</a>

  • Alternative codes found

    RIV/60162694:G44__/15:43875482

  • Result on the web

    <a href="http://actamedica.lfhk.cuni.cz/media/pdf/am_2015058010021.pdf" target="_blank" >http://actamedica.lfhk.cuni.cz/media/pdf/am_2015058010021.pdf</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.14712/18059694.2015.87" target="_blank" >10.14712/18059694.2015.87</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Melatonin Regulates Oxidative Stress Initiated by Freund's Complete Adjuvant

  • Original language description

    Melatonin is a hormone with strong antioxidant properties. In this experiment, Freund's complete adjuvant was used as a stressogenic substance given to laboratory outbred mice, whereas melatonin was investigated as a protectant against the stressogenic effect. Levels of low molecular weight antioxidants, thiobarbituric acid reactive substances, and tumor necrosis factor α and activity of glutathione reductase were determined in blood from the animals. Surprisingly, melatonin was not involved in direct regulation of antioxidants, thiobarbituric acid reactive substances and tumor necrosis factor α. On the other hand, melatonin regulated glutathione reductase activity. We can conclude on regulation of metabolism caused by melatonin in the model. The effect was more important than the expected regulation of immunity and basal oxidative homeostasis.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EC - Immunology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: Central european institute of technology</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Acta Medica Hradec Kralove

  • ISSN

    1211-4286

  • e-ISSN

  • Volume of the periodical

    58

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    4

  • Pages from-to

    21-24

  • UT code for WoS article

  • EID of the result in the Scopus database