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Sarcosine up-regulates expression of genes involved in cell cycle progression of metastatic models of prostate cancer

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F16%3A00092048" target="_blank" >RIV/62156489:43210/16:00092048 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216305:26620/16:PU122875

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Sarcosine up-regulates expression of genes involved in cell cycle progression of metastatic models of prostate cancer

  • Original language description

    In Europe, prostate cancer (PCa) is the most common solid neoplasm[1]. More than one thousand men in Czech Republic die due to this dinase every year[2]. Sarcosine, an intermediate and byproduct in glycine metabolism, represents a potential urinary biomarker exploitable for early PCa diagnosis. It also acts as potential oncometabolite. Thus, we investigated the effect of sarcosine treatment on behavior of PCa tumors in vivo.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA16-18917S" target="_blank" >GA16-18917S: The study of sarcosine metabolism and its participation in prostate cancer development</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů