Electrochemical sensing of etoposide using carbon quantum dot modified glassy carbon electrode

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F16%3A43909260" target="_blank" >RIV/62156489:43210/16:43909260 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/16:10323528 RIV/00216208:11130/16:10323528 RIV/00216224:14110/16:00091188 RIV/00216305:26620/16:PU120444 RIV/00064203:_____/16:10323528
Result on the web
<a href="http://dx.doi.org/10.1039/c5an02476e" target="_blank" >http://dx.doi.org/10.1039/c5an02476e</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/c5an02476e" target="_blank" >10.1039/c5an02476e</a>

Result language
angličtina
Original language name
Electrochemical sensing of etoposide using carbon quantum dot modified glassy carbon electrode
Original language description
In this study, enhancement of the electrochemical signals of etoposide (ETO) measured by differential pulse voltammetry (DPV) by modifying a glassy carbon electrode (GCE) with carbon quantum dots (CQDs) is demonstrated. In comparison with a bare GCE, the modified GCE exhibited a higher sensitivity towards electrochemical detection of ETO. The lowest limit of detection was observed to be 5 nM ETO. Furthermore, scanning electron microscopy (SEM), fluorescence microscopy (FM), and electrochemical impedance spectroscopy (EIS) were employed for the further study of the working electrode surface after the modification with CQDs. Finally, the GCE modified with CQDs under optimized conditions was used to analyse real samples of ETO in the prostate cancer cell line PC3. After different incubation times (1, 3, 6, 9, 12, 18 and 24 h), these samples were then prepared prior to electrochemical detection by the GCE modified with CQDs. High performance liquid chromatography with an electrochemical detection method was employed to verify the results from the GCE modified with CQDs.
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
—

Project
<a href="/en/project/GA14-18344S" target="_blank" >GA14-18344S: Development of nanoparticle-based cytostatics and enzymes for enhanced chemotherapy of human neuroblastomas and study of mechanisms of their action</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)