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The Influence of Zinc Nanocomplexes on Antioxidant Potential of the Organism

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F16%3A43910143" target="_blank" >RIV/62156489:43210/16:43910143 - isvavai.cz</a>

  • Result on the web

    <a href="https://mnet.mendelu.cz/mendelnet2016/mnet_2016_full.pdf" target="_blank" >https://mnet.mendelu.cz/mendelnet2016/mnet_2016_full.pdf</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The Influence of Zinc Nanocomplexes on Antioxidant Potential of the Organism

  • Original language description

    The aim of our experiment was to find out if a new forms of zinc based on nanotechnology, can increase the antioxidant state in laboratory rats. The male of outbred Wistar albino rats strain were used in this experiment. The rats were sorted out to the three groups. In each of group were stabled 6 males. The first control group (Control) (n = 6) was not fed with higher doses of zinc. The second group (ZnEDT) of rats (n = 6) was fed with zinc nanoparticles chelated by ethylenediaminetetraacetic acid (EDTA) (200 mg/kg of diet). The third group (ZnNTA) of rats (n = 6) was fed with zinc nanoparticles chelated by nitrilotriacetic acid (NTA) (200 mg/kg of diet). After 15 days of zinc nanoparticles exposure, the rats were sacrificed. Immediately, the samples of blood and liver were analyzed. As markers of oxidative potential of organism were used antioxidant activity determined using FR method, level of superoxiddismutase and methallothionein and finally, content of total zinc determined by atomic absorption spectrometry (AAS). The nanozinc supplementation shows the influence on studied parameters. Our results proved the rat organism is sensitive on the used zinc nanocomplexes.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    GH - Nutrition of farm animals

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    MendelNet 2016: Proceedings of International PhD Students Conference

  • ISBN

    978-80-7509-443-8

  • ISSN

  • e-ISSN

  • Number of pages

    1

  • Pages from-to

    824-828

  • Publisher name

    Mendelova univerzita v Brně

  • Place of publication

    Brno

  • Event location

    Brno

  • Event date

    Nov 9, 2016

  • Type of event by nationality

    EUR - Evropská akce

  • UT code for WoS article

    000392968500148