Influence of milk thistle pressed parts on rats liver histology

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F18%3A43913268" target="_blank" >RIV/62156489:43210/18:43913268 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.5219/864" target="_blank" >https://doi.org/10.5219/864</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5219/864" target="_blank" >10.5219/864</a>

Result language

angličtina

Original language name

Influence of milk thistle pressed parts on rats liver histology

Original language description

Milk thistle (Silybum marianum) is one of the best known and very often used herbs with positive effect on liver. The aim of this article was to study influence of addition of milk thistle pressed parts in feed ration on liver histology and weight increase of laboratory rats. The experiment was tested by 15 pieces of laboratory rats divided into 3 groups (A, B, C). The rats in first group (A) hade feed ration with addition of 10% milk thistle pressed parts, second group (B) hade feed ration with 20% and control group (C) hade feed ration without addition of milk thistle pressed parts. The silymarin content of pressed milk thistle seed was 26.2 mg/g. The aim of this article is to study influence of addition of milk thistle pressed parts in feed ration on liver histology and weight increase of laboratory rats. The hypothesis is that the feeding addition - milk thistle seed pressed parts has positive effect on weight performance and liver histology. Does the feeding addition have any effect on these health indicators? Does feeding of milk thistle seed pressed parts have any sense? In results, the groups with addition of milk thistle had significant bigger average gain increases than the control group. Histological results vary considerably among groups of rats. All rats in the control group had dystrophic liver with sinusoidal congestion. In most rats of the group A, the dystrophy was minimal without congestion. On the other hand, most of rats of the group B had liver dystrophy caused by large droplets steatosis with congestion. All rats in control group C were found to have significant dystrophy caused by steatosis. The results indicate rats receiving the addition of milk thistle pressed parts in their feed had a lower incidence of liver steatosis due to the hepatoprotective effects of silymarin.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

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OECD FORD branch

40500 - Other agricultural sciences

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Potravinárstvo

ISSN

1338-0230

e-ISSN

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Volume of the periodical

12

Issue of the periodical within the volume

1

Country of publishing house

SK - SLOVAKIA

Number of pages

7

Pages from-to

33-39

UT code for WoS article

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EID of the result in the Scopus database

2-s2.0-85041514377