Oxidative stress response of rainbow trout (Oncorhynchus mykiss) to multiple stressors

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F18%3A43913864" target="_blank" >RIV/62156489:43210/18:43913864 - isvavai.cz</a>

Alternative codes found

RIV/60162694:G44__/18:43889526 RIV/62157124:16270/18:43877107

Result on the web

<a href="https://doi.org/10.2754/avb201887010055" target="_blank" >https://doi.org/10.2754/avb201887010055</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2754/avb201887010055" target="_blank" >10.2754/avb201887010055</a>

Result language

angličtina

Original language name

Oxidative stress response of rainbow trout (Oncorhynchus mykiss) to multiple stressors

Original language description

Fish can be exposed to multiple stressors at the same time, including natural toxins, environmental pollutants or feed contamination. In this study, we report on the effects of controlled exposure of rainbow trout (Oncorhynchus mykiss) to multiple stressors. In doing so, we test the hypothesis that cyanobacterial biomass and arsenic in feed combine to enhance negative effects on fish, including modulation of antioxidant response. The trout (mean weight 288 +/- 59 g) were divided into six experimental groups of 25 fish each (C - control group; B - 3% lyophilised toxic cyanobacterial biomass; As5 - arsenic at 5 mg.kg(-1); As50 - arsenic at 50 mg.kg(-1); and two combinations of cyanobacterial biomass and arsenic (B + As5 and B + As50). All indicators of oxidative stress were determined using standard methods, showing significant changes. Overall antioxidant capacity (ferric reducing antioxidant power) decreased significantly in the liver, gills and heart after 10-days, while lipid peroxidation (thiobarbituric acid reactive substances) increased in the liver of groups exposed to cyanobacterial biomass, and in the heart of groups exposed to increased concentrations of arsenic and those under combined exposure. Levels of glutathione reductase showed a significant reduction following exposure, especially in the gills and liver. Our results indicate that the antioxidant system plays an important role in the protective response of tissues to stressors, and especially arsenic.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

40301 - Veterinary science

Project

<a href="/en/project/QJ1510077" target="_blank" >QJ1510077: Increasing and more efficient production of salmonids in the Czech Republic using their genetic identification.</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta Veterinaria Brno

ISSN

0001-7213

e-ISSN

—

Volume of the periodical

87

Issue of the periodical within the volume

1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

10

Pages from-to

55-64

UT code for WoS article

000431956300007

EID of the result in the Scopus database

2-s2.0-85045403676