Prevalence of cervical human papillomavirus is associated with p16 expression and irregular menstrual cycles among married Jordanian women

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F18%3A43914310" target="_blank" >RIV/62156489:43210/18:43914310 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.12892/ejgo4318.2018" target="_blank" >http://dx.doi.org/10.12892/ejgo4318.2018</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.12892/ejgo4318.2018" target="_blank" >10.12892/ejgo4318.2018</a>

Result language

angličtina

Original language name

Prevalence of cervical human papillomavirus is associated with p16 expression and irregular menstrual cycles among married Jordanian women

Original language description

Persistent infection with high-risk human papillomavirus (HPV) is the leading cause of cervical cancer worldwide. In this study, we used immunohistochemical methods to investigate the prevalence of HPV among Jordanian women who visited local gynaecological clinics. Expression of HPV and p16 protein was analysed to assess the high-risk prevalence of the virus. Accordingly, HPV was positively expressed in 41% (57 out of 140) of the cases and expression of p16 was found in 28% (39 out of 140) of the cases. Factor analysis showed that irregular cycles increased the chances of HPV by 13.342-fold (p = 0.001) and p16 expression by 17.091-fold (p &lt; 0.001). Age-adjusted odds ratios were 12.923-fold for HPV (p = 0.002) and 16.986-fold for p16 expression (p &lt; 0.001). In conclusion, awareness, screening, and vaccination are key preventive measures in the fight against HPV and cervical cancer are important in conservative countries such as Jordan.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30204 - Oncology

Project

<a href="/en/project/LQ1601" target="_blank" >LQ1601: CEITEC 2020</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Journal of Gynaecological Oncology

ISSN

0392-2936

e-ISSN

—

Volume of the periodical

39

Issue of the periodical within the volume

5

Country of publishing house

CA - CANADA

Number of pages

7

Pages from-to

779-785

UT code for WoS article

000444420100017

EID of the result in the Scopus database

2-s2.0-85053315104