Application of molecularly imprinted polymers as artificial receptors for imaging

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F20%3A43916730" target="_blank" >RIV/62156489:43210/20:43916730 - isvavai.cz</a>

Alternative codes found

RIV/00216305:26620/20:PU134864

Result on the web

<a href="https://doi.org/10.1016/j.actbio.2019.11.007" target="_blank" >https://doi.org/10.1016/j.actbio.2019.11.007</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.actbio.2019.11.007" target="_blank" >10.1016/j.actbio.2019.11.007</a>

Result language

angličtina

Original language name

Application of molecularly imprinted polymers as artificial receptors for imaging

Original language description

Medical diagnostics aims at specific localization of molecular targets as well as detection of abnormalities associated with numerous diseases. Molecularly imprinted polymers (MIPs) represent an approach of creating a synthetic material exhibiting selective recognition properties toward the desired template. The fabricated target-specific MIPs are usually well reproducible, economically efficient, and stable under critical conditions as compared to routinely used biorecognition elements such as fluorescent proteins, antibodies, enzymes, or aptamers and can even be created to those targets for which no antibodies are available. In this review, we summarize the methods of polymer fabrication. Further, we provide key for selection of the core material with imaging function depending on the imaging modality used. Finally, MIP-based imaging applications are highlighted and presented in a comprehensive form from different aspects. Statement of significance: In this review, we summarize the methods of polymer fabrication. Key applications of Molecularly imprinted polymers (MIPs) in imaging are highlighted and discussed with regard to the selection of the core material for imaging as well as commonly used imaging targets. MIPs represent an approach of creating a synthetic material exhibiting selective recognition properties toward the desired template. The fabricated target-specific MIPs are usually well reproducible, economically efficient, and stable under critical conditions as compared to routinely used biorecognition elements, e.g., antibodies, fluorescent proteins, enzymes, or aptamers, and can even be created to those targets for which no antibodies are available.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta Biomaterialia

ISSN

1742-7061

e-ISSN

—

Volume of the periodical

101

Issue of the periodical within the volume

1 January

Country of publishing house

GB - UNITED KINGDOM

Number of pages

15

Pages from-to

444-458

UT code for WoS article

000504504300035

EID of the result in the Scopus database

2-s2.0-85075388236