Caveolin-1 in oncogenic metabolic symbiosis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F20%3A43917806" target="_blank" >RIV/62156489:43210/20:43917806 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/20:00114233 RIV/00216208:11110/20:10413728
Result on the web
<a href="https://doi.org/10.1002/ijc.32987" target="_blank" >https://doi.org/10.1002/ijc.32987</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/ijc.32987" target="_blank" >10.1002/ijc.32987</a>
Alternative languages
Result language
angličtina
Original language name
Caveolin-1 in oncogenic metabolic symbiosis
Original language description
Metabolic phenotypes of cancer cells are heterogeneous and flexible as a tumor mass is a hurriedly evolving system capable of constant adaptation to oxygen and nutrient availability. The exact type of cancer metabolism arises from the combined effects of factors intrinsic to the cancer cells and factors proposed by the tumor microenvironment. As a result, a condition termed oncogenic metabolic symbiosis in which components of the tumor microenvironment (TME) promote tumor growth often occurs. Understanding how oncogenic metabolic symbiosis emerges and evolves is crucial for perceiving tumorigenesis. The process by which tumor cells reprogram their TME involves many mechanisms, including changes in intercellular communication, alterations in metabolic phenotypes of TME cells, and rearrangement of the extracellular matrix. It is possible that one molecule with a pleiotropic effect such as Caveolin-1 may affect many of these pathways. Here, we discuss the significance of Caveolin-1 in establishing metabolic symbiosis in TME.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Cancer
ISSN
0020-7136
e-ISSN
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Volume of the periodical
147
Issue of the periodical within the volume
7
Country of publishing house
US - UNITED STATES
Number of pages
15
Pages from-to
1793-1807
UT code for WoS article
000527026700001
EID of the result in the Scopus database
2-s2.0-85083676157