Chiral conazole fungicides - (Enantioselective) terrestrial bioaccumulation and aquatic toxicity

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F20%3A43918130" target="_blank" >RIV/62156489:43210/20:43918130 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14310/20:00117361

Result on the web

<a href="https://doi.org/10.1016/j.scitotenv.2020.140821" target="_blank" >https://doi.org/10.1016/j.scitotenv.2020.140821</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.scitotenv.2020.140821" target="_blank" >10.1016/j.scitotenv.2020.140821</a>

Result language

angličtina

Original language name

Chiral conazole fungicides - (Enantioselective) terrestrial bioaccumulation and aquatic toxicity

Original language description

Five conazole fungicides (CFs) (epoxiconazole, tebuconazole, myclobutanil, uniconazole (P), rac-uniconazole, and diniconazole) were tested in order to provide additional information on i) the effects of CFs on the nematode Caenorhabditis elegans and on the aquatic insect Chironomus riparius under acute exposure scenarios and in multi-generation exposure studies, taking advantage of the short life cycle of nematodes and ii) on the bioaccumulation (earthworm Eisenia andrei) profiles of CFs including also the enantiomer-specific assessment of degradation in soils and uptake/elimination by earthworms. Acute toxicity was considered low following the exposure of up to 2.5 mg of CFs per liter of the test medium. In a multigeneration study on nematodes, all five generations exposed to epoxiconazole were significantly negatively affected in terms of reproductive efficiency, and the severity of effects increased from F0 to F1 generation and was sustained thereafter. Adverse effects were also observed in the case of uniconazole (P) and diniconazole, and similarly to epoxiconazole, the effects occurred within the active life of the pesticides and were assumed to be based on their half-lives in soil (e.g., 53.3 to 691 days for uniconazole and diniconazole in our study) and in sediment/water. Bioaccumulation of diniconazole and uniconazole by earthworms varied between soils (Lufa 2.1 GREATER-THAN OR EQUAL TO Lufa 2.4 &gt; sandy soil &gt; Lufa 2.2) and compounds (diniconazole &gt; uniconazole) and was enantioselective. Earthworms preferentially accumulated R-uniconazole as a result of faster elimination of the S-form, which was evidenced from the enantiomer-specific uptake/elimination rate constants derived from the bioaccumulation profiles. Our results suggest that multigeneration exposure studies can advantageously be used for assessing the long-term and trans-general effects of pesticides. Also, the enantioselectivity in bioaccumulation observed for both uniconazole and diniconazole suggests that enantioselectivity in the fate and effects should be considered when exploring ways for safer and sustainable use of chiral pesticides.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

40106 - Agronomy, plant breeding and plant protection; (Agricultural biotechnology to be 4.4)

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Science of the Total Environment

ISSN

0048-9697

e-ISSN

—

Volume of the periodical

743

Issue of the periodical within the volume

15 November

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

12

Pages from-to

140821

UT code for WoS article

000573543300017

EID of the result in the Scopus database

2-s2.0-85087752614